DOP1A Gene Summary [Human]

Predicted to be involved in Golgi to endosome transport and endoplasmic reticulum organization. Predicted to be located in Golgi membrane. Predicted to be active in endosome and trans-Golgi network. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
DOP1A
Official Name
DOP1 leucine zipper like protein A [Source:HGNC Symbol;Acc:HGNC:21194]
Ensembl ID
ENSG00000083097
Bio databases IDs NCBI: 23033 Ensembl: ENSG00000083097
Aliases DOP1 leucine zipper like protein A
Synonyms B130005I07RIK, BC035275, C130028L17, D9Ertd809e, dJ202D23.2, DOP1, DOP1 leucine zipper like protein A, DOPEY1, KIAA1117, RGD1305534
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human DOP1A often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Dopey, N-terminal

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • schizophrenia
  • neoplasia
  • organismal death
  • gastric cancer
  • bipolar disorder
regulated by
  • HFE-145 cells
  • CagA
  • AGS cells
role in cell
  • expression in
  • proliferation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Golgi Apparatus

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human DOP1A gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein transport
  • Golgi to endosome transport

Cellular Component

Where in the cell the gene product is active
  • trans-Golgi network
  • endosome
  • cytosol
  • Golgi membrane
  • Golgi-associated vesicle

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.