CMTM1 Gene Summary [Human]

This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules. The protein encoded by this gene may play an important role in testicular development. Alternatively spliced transcript variants encoding different isoforms have been identified. Naturally occurring read-through transcription occurs between this locus and the neighboring locus CKLF (chemokine-like factor).[provided by RefSeq, Feb 2011]

Details

Type
Protein Coding
Official Symbol
CMTM1
Official Name
CKLF like MARVEL transmembrane domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19172]
Ensembl ID
ENSG00000089505
Bio databases IDs NCBI: 113540 Ensembl: ENSG00000089505
Aliases CKLF like MARVEL transmembrane domain containing 1
Synonyms CHLFH1a, CKLFH, CKLFH1, CKLF-like MARVEL transmembrane domain containing 1, CKLFSF1
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CMTM1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Membrane-associating domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human CMTM1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • chemotaxis
  • signal transduction

Cellular Component

Where in the cell the gene product is active
  • extracellular space
  • membrane

Molecular Function

What the gene product does at the molecular level
  • cytokine activity

Gene-Specific Assays for Results You Can Trust

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