SLC25A17 Gene Summary [Human]

This gene encodes a peroxisomal membrane protein that belongs to the family of mitochondrial solute carriers. It is expressed in the liver, and is likely involved in transport. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Details

Type
Nonsense Mediated Decay
Official Symbol
SLC25A17
Official Name
solute carrier family 25 member 17 [Source:HGNC Symbol;Acc:HGNC:10987]
Ensembl ID
ENSG00000100372
Bio databases IDs NCBI: 10478 Ensembl: ENSG00000100372
Aliases solute carrier family 25 member 17, peroxisomal membrane protein (34kD)
Synonyms PMP34, PMP47, solute carrier family 25 member 17, solute carrier family 25 (mitochondrial carrier, peroxisomal membrane protein), member 17
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SLC25A17 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Mitochondrial carrier protein
  • protein binding
  • organic anion transporter
  • nucleotide transporter
  • purine ribonucleotide transporter
  • ADP transporter
  • organic cation transporter
  • ATP transporter
  • adenine nucleotide transporter
  • flavin-adenine dinucleotide transporter
  • coenzyme A transporter
  • chaperone binding
  • transporter

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • bipolar disorder
  • bipolar I disorder
regulated by
regulates
  • adenosine triphosphate
  • fatty acid
  • nucleotide

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • membrane fraction
  • cytosol
  • peroxisome membrane
  • peroxisomes

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human SLC25A17 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • NAD transmembrane transport
  • fatty acid beta-oxidation
  • fatty acid transport
  • FAD transmembrane transport
  • AMP transport
  • coenzyme A transmembrane transport
  • ATP transport
  • transport
  • fatty acid alpha-oxidation
  • ADP transport

Cellular Component

Where in the cell the gene product is active
  • peroxisomal membrane
  • peroxisome
  • membrane
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • adenine nucleotide transmembrane transporter activity
  • antiporter activity
  • FAD transmembrane transporter activity
  • chaperone binding
  • AMP transmembrane transporter activity
  • FMN transmembrane transporter activity
  • coenzyme A transmembrane transporter activity
  • NAD transporter activity
  • ADP transmembrane transporter activity
  • ATP transmembrane transporter activity

Gene-Specific Assays for Results You Can Trust

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