ZBED4 Gene Summary [Human]

Enables identical protein binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
ZBED4
Official Name
zinc finger BED-type containing 4 [Source:HGNC Symbol;Acc:HGNC:20721]
Ensembl ID
ENSG00000100426
Bio databases IDs NCBI: 9889 Ensembl: ENSG00000100426
Aliases zinc finger BED-type containing 4
Synonyms 1700009F06RIK, LOC223773, LOC678931, zinc finger BED-type containing 4, zinc finger, BED-type containing 4
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ZBED4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • RNA polymerase II transcription regulatory region sequence-specific binding transcriptional activator activity
  • RNA polymerase II transcription factor activity, sequence-specific DNA binding
  • transcription regulator
  • nucleic acid binding
  • double-stranded DNA binding
  • BED zinc finger
  • hAT family C-terminal dimerization region
  • protein binding
  • sequence-specific DNA binding
  • identical protein binding
  • RNA binding
  • hATC domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • schizophrenia
regulated by
regulates
  • DNA endogenous promoter
  • DNA promoter
  • RNA polymerase II

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • Cytoplasm
  • nucleoplasm
  • chromatin

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human ZBED4 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • positive regulation of transcription from RNA polymerase II promoter

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm
  • photoreceptor inner segment
  • chromatin
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • identical protein binding
  • protein binding
  • RNA binding
  • metal ion binding
  • RNA polymerase II regulatory region sequence-specific DNA binding
  • transcription regulatory region sequence-specific DNA binding
  • protein dimerization activity
  • RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
  • sequence-specific DNA binding RNA polymerase II transcription factor activity

Gene-Specific Assays for Results You Can Trust

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