RABGGTA Gene Summary [Human]
Predicted to enable small GTPase binding activity. Predicted to contribute to Rab geranylgeranyltransferase activity. Predicted to be involved in protein geranylgeranylation. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Retained Intron |
| Official Symbol | RABGGTA |
| Official Name | Rab geranylgeranyltransferase subunit alpha [Source:HGNC Symbol;Acc:HGNC:9795] |
| Ensembl ID | ENSG00000100949 |
| Bio databases IDs | |
| Aliases | Rab geranylgeranyltransferase subunit alpha, protein prenyltransferase alpha subunit repeat containing 3 |
| Synonyms | GGT2 alpha, GGT2 α, GGTase II α, gm, PTAR3, RAB GERANYLGERANYL TRANSFERASE alpha, Rab geranylgeranyl transferase, a subunit, Rab geranylgeranyltransferase subunit alpha, Rab geranylgeranyltransferase subunit α, RAB GERANYLGERANYL TRANSFERASE α, RABGGT alpha, RAB GG Transferase Component A, RABGGT α, α RabGGTase |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RABGGTA often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Protein prenyltransferase alpha subunit repeat
- enzyme binding
- Leucine rich repeat
- Rab geranylgeranyl transferase alpha-subunit, insert domain
- enzyme
- protein binding
- Leucine Rich repeats (2 copies)
- RAB-protein geranylgeranyltransferase
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Plasma Membrane
- cytosol
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RABGGTA gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein modification process
- protein geranylgeranylation
- visual perception
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- Rab-protein geranylgeranyltransferase complex
- cytosol
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- zinc ion binding
- protein binding
- small GTPase binding
- Rab geranylgeranyltransferase activity