Rabggta Gene Summary [Mouse]
Enables Rab geranylgeranyltransferase activity. Acts upstream of or within protein geranylgeranylation. Predicted to be part of Rab-protein geranylgeranyltransferase complex. Predicted to be active in cytoplasm. Used to study Hermansky-Pudlak syndrome. Orthologous to human RABGGTA (Rab geranylgeranyltransferase subunit alpha). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rabggta |
| Official Name | Rab geranylgeranyl transferase, a subunit [Source:MGI Symbol;Acc:MGI:1860443] |
| Ensembl ID | ENSMUSG00000040472 |
| Bio databases IDs | |
| Aliases | Rab geranylgeranyl transferase, a subunit |
| Synonyms | GGT2 alpha, GGT2 α, GGTase II α, gm, PTAR3, RAB GERANYLGERANYL TRANSFERASE alpha, Rab geranylgeranyl transferase, a subunit, Rab geranylgeranyltransferase subunit alpha, Rab geranylgeranyltransferase subunit α, RAB GERANYLGERANYL TRANSFERASE α, RABGGT alpha, RAB GG Transferase Component A, RABGGT α, α RabGGTase |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rabggta often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Protein prenyltransferase alpha subunit repeat
- enzyme binding
- Leucine rich repeat
- Rab geranylgeranyl transferase alpha-subunit, insert domain
- enzyme
- protein binding
- Leucine Rich repeats (2 copies)
- RAB-protein geranylgeranyltransferase
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Plasma Membrane
- cytosol
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rabggta gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein modification process
- protein geranylgeranylation
- visual perception
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- Rab-protein geranylgeranyltransferase complex
- cytosol
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- zinc ion binding
- protein binding
- small GTPase binding
- Rab geranylgeranyltransferase activity