Rabggta Gene Summary [Rat]

Enables Rab geranylgeranyltransferase activity and small GTPase binding activity. Involved in protein geranylgeranylation. Part of Rab-protein geranylgeranyltransferase complex. Orthologous to human RABGGTA (Rab geranylgeranyltransferase subunit alpha). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Rabggta
Official Name
Rab geranylgeranyltransferase subunit alpha [Source:RGD Symbol;Acc:621697]
Ensembl ID
ENSRNOG00000030483
Bio databases IDs NCBI: 58983 Ensembl: ENSRNOG00000030483
Aliases Rab geranylgeranyltransferase subunit alpha
Synonyms GGT2 alpha, GGT2 α, GGTase II α, gm, PTAR3, RAB GERANYLGERANYL TRANSFERASE alpha, Rab geranylgeranyl transferase, a subunit, Rab geranylgeranyltransferase subunit alpha, Rab geranylgeranyltransferase subunit α, RAB GERANYLGERANYL TRANSFERASE α, RABGGT alpha, RAB GG Transferase Component A, RABGGT α, α RabGGTase
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Rabggta often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Protein prenyltransferase alpha subunit repeat
  • enzyme binding
  • Leucine rich repeat
  • Rab geranylgeranyl transferase alpha-subunit, insert domain
  • enzyme
  • protein binding
  • Leucine Rich repeats (2 copies)
  • RAB-protein geranylgeranyltransferase

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • keratocystic odontogenic tumor
  • keratocystic odontogenic tumors
  • choroideremia
regulated by
role in cell
  • apoptosis
  • growth

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • Plasma Membrane
  • cytosol
  • plasma

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Rabggta gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein modification process
  • protein geranylgeranylation
  • visual perception

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • Rab-protein geranylgeranyltransferase complex
  • cytosol
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • zinc ion binding
  • protein binding
  • small GTPase binding
  • Rab geranylgeranyltransferase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.