LUZP4 Gene Summary [Human]

This gene encodes a leucine-zipper protein that was first defined as a cancer testis antigens. The encoded protein is an RNA binding protein that interacts with the mRNA export receptor nuclear RNA export factor 2. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

Details

Type
Protein Coding
Official Symbol
LUZP4
Official Name
leucine zipper protein 4 [Source:HGNC Symbol;Acc:HGNC:24971]
Ensembl ID
ENSG00000102021
Bio databases IDs NCBI: 51213 Ensembl: ENSG00000102021
Aliases leucine zipper protein 4, cancer/testis antigen 28
Synonyms CT-28, CT-8, HOM-TES-85, leucine zipper protein 4
Species
Human, Homo sapiens

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human LUZP4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • alveolar soft part sarcoma
  • soft tissue sarcoma cancer

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nuclear envelope

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human LUZP4 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • mRNA transport

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • RNA binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.