CD99L2 Gene Summary [Human]
This gene encodes a cell-surface protein that is similar to CD99. A similar protein in mouse functions as an adhesion molecule during leukocyte extravasation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | CD99L2 |
| Official Name | CD99 molecule like 2 [Source:HGNC Symbol;Acc:HGNC:18237] |
| Ensembl ID | ENSG00000102181 |
| Bio databases IDs | |
| Aliases | CD99 molecule like 2 |
| Synonyms | CD99 antigen-like 2, CD99B, CD99 molecule-like 2, LOC100911604, LOC100912979, LOC686985, LOC691632, MIC2L1, vms-tm2, Xap89 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CD99L2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- CD99 antigen like protein 2
- extracellular domain
- protein binding
- ACT domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
- cell borders
- perinuclear region
- Golgi Apparatus
- cell-cell contacts
- granules
- cell-cell adherens junctions
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CD99L2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of neutrophil extravasation
- diapedesis
- positive regulation of T cell extravasation
- cell adhesion
Cellular Component
Where in the cell the gene product is active
- adherens junction
- focal adhesion
- extracellular region
- plasma membrane
- cell surface
Molecular Function
What the gene product does at the molecular level
- protein binding