Cd99l2 Gene Summary [Mouse]
Acts upstream of or within diapedesis; positive regulation of T cell extravasation; and positive regulation of neutrophil extravasation. Located in adherens junction and cell surface. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system; nervous system; and skin. Orthologous to human CD99L2 (CD99 molecule like 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cd99l2 |
| Official Name | CD99 antigen-like 2 [Source:MGI Symbol;Acc:MGI:2177151] |
| Ensembl ID | ENSMUSG00000035776 |
| Bio databases IDs | |
| Aliases | CD99 antigen-like 2 |
| Synonyms | CD99 antigen-like 2, CD99B, CD99 molecule-like 2, LOC100911604, LOC100912979, LOC686985, LOC691632, MIC2L1, vms-tm2, Xap89 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cd99l2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- CD99 antigen like protein 2
- extracellular domain
- protein binding
- ACT domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
- cell borders
- perinuclear region
- Golgi Apparatus
- cell-cell contacts
- granules
- cell-cell adherens junctions
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cd99l2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of neutrophil extravasation
- diapedesis
- positive regulation of T cell extravasation
- cell adhesion
Cellular Component
Where in the cell the gene product is active
- adherens junction
- focal adhesion
- extracellular region
- plasma membrane
- cell surface
Molecular Function
What the gene product does at the molecular level
- protein binding