JADE3 Gene Summary [Human]
This gene encodes a member of a family of large proteins containing PHD (plant homeo domain)-type zinc fingers. The encoded protein may be associated in a nuclear complex that functions in histone H4 acetylation. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2013]
Details
| Type | Protein Coding |
| Official Symbol | JADE3 |
| Official Name | jade family PHD finger 3 [Source:HGNC Symbol;Acc:HGNC:22982] |
| Ensembl ID | ENSG00000102221 |
| Bio databases IDs | |
| Aliases | jade family PHD finger 3 |
| Synonyms | 5730598B06, AI851988, jade family PHD finger 3, KIAA0215, mKIAA0215, PHF16, RGD1563945 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human JADE3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- PHD zinc finger
- PHD-like zinc-binding domain
- PHD finger superfamily
- protein binding
- PHD-zinc-finger like domain
- PHD-finger
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human JADE3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of cell growth
- regulation of DNA biosynthetic process
- regulation of transcription, DNA-dependent
- regulation of DNA replication
- regulation of cell cycle
- regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nucleoplasm
- histone acetyltransferase complex
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding