STX10 Gene Summary [Human]
This gene belongs to the syntaxin family and encodes a soluble N-ethylmaleimide sensitive factor attachment protein receptor (SNARE). The encoded protein is involved in docking and fusion events at the Golgi apparatus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | STX10 |
| Official Name | syntaxin 10 [Source:HGNC Symbol;Acc:HGNC:11428] |
| Ensembl ID | ENSG00000104915 |
| Bio databases IDs | |
| Aliases | syntaxin 10 |
| Synonyms | hsyn10, SYN10, syntaxin 10 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human STX10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Syntaxin 6, N-terminal
- Helical region found in SNAREs
- N-terminal domain of syntaxin-6 and similar proteins
- protein binding
- SNARE motif
- syntaxin binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- perinuclear region
- vesicles
- Golgi membrane
- trans Golgi network
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human STX10 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of protein localization
- vesicle fusion
- vesicle docking
- early endosome to Golgi transport
- retrograde transport, endosome to Golgi
- intracellular protein transport
Cellular Component
Where in the cell the gene product is active
- trans-Golgi network
- perinuclear region of cytoplasm
- vesicle
- endomembrane system
- cytosol
- SNARE complex
- Golgi membrane
- synaptic vesicle membrane
- trans-Golgi network membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- syntaxin binding
- SNAP receptor activity
- SNARE binding