ATP13A1 Gene Summary [Human]
Enables transmembrane protein dislocase activity. Involved in extraction of mislocalized protein from ER membrane. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Retained Intron |
| Official Symbol | ATP13A1 |
| Official Name | ATPase 13A1 [Source:HGNC Symbol;Acc:HGNC:24215] |
| Ensembl ID | ENSG00000105726 |
| Bio databases IDs | |
| Aliases | ATPase 13A1, cation transporting ATPase |
| Synonyms | ATP13A, ATPase 13A1, ATPase type 13A1, catp, CGI-152 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ATP13A1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- manganese-transporting ATPase
- heavy metal translocating P-type ATPase
- protein binding
- E1-E2 ATPase
- Cation transport ATPase (P-type)
- P-type ATPase of unknown pump specificity (type V)
- Haloacid Dehalogenase-like Hydrolases
- copper-(or silver)-translocating P-type ATPase
- ATPase, P-type (transporting), HAD superfamily, subfamily IC
- transporter
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cellular membrane
- endoplasmic reticulum membrane
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ATP13A1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- transmembrane transport
- manganese ion transmembrane transport
- ion transmembrane transport
- protein transport
- cellular calcium ion homeostasis
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- membrane
Molecular Function
What the gene product does at the molecular level
- ATPase activity
- ATP binding
- manganese-transporting ATPase activity
- ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
- cation-transporting ATPase activity
- metal ion binding