TPRA1 Gene Summary [Human]
Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within embryonic cleavage and negative regulation of mitotic cell cycle phase transition. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | TPRA1 |
| Official Name | transmembrane protein adipocyte associated 1 [Source:HGNC Symbol;Acc:HGNC:30413] |
| Ensembl ID | ENSG00000163870 |
| Bio databases IDs | |
| Aliases | transmembrane protein adipocyte associated 1, transmembrane protein 227 |
| Synonyms | GPR175, LOC51210, TMEM227, TPRA40, transmembrane protein, adipocyte asscociated 1, transmembrane protein adipocyte associated 1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TPRA1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-protein coupled receptor
- Predicted membrane protein
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TPRA1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- embryonic cleavage
- G-protein coupled receptor signaling pathway
- lipid metabolic process
Cellular Component
Where in the cell the gene product is active
- membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- G-protein coupled receptor activity
- protein binding