DRG2 Gene Summary [Human]
This gene encodes a GTP-binding protein known to function in the regulation of cell growth and differentiation. Read-through transcripts containing this gene and a downstream gene have been identified, but they are not thought to encode a fusion protein. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jan 2012]
Details
| Type | Protein Coding |
| Official Symbol | DRG2 |
| Official Name | developmentally regulated GTP binding protein 2 [Source:HGNC Symbol;Acc:HGNC:3030] |
| Ensembl ID | ENSG00000108591 |
| Bio databases IDs | |
| Aliases | developmentally regulated GTP binding protein 2 |
| Synonyms | developmentally regulated GTP binding protein 2, RGD1562380 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human DRG2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- GTP binding
- TGS domain
- small GTP-binding protein domain
- Ubl1_cv_Nsp3_N-like
- 50S ribosome-binding GTPase
- GTPase
- enzyme
- protein binding
- C-terminal region of MMR_HSR1 domain
- P-loop containing Nucleoside Triphosphate Hydrolases
- RNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intracellular membrane-bounded organelle
- Nucleus
- cytosol
- nucleoplasm
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human DRG2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- signal transduction
- cytoplasmic translation
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- intracellular membrane-bounded organelle
- membrane
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- GTP binding
- RNA binding
- protein binding
- metal ion binding
- GTPase activity