Drg2 Gene Summary [Rat]

Predicted to enable GTPase activity and RNA binding activity. Predicted to be located in cytosol and nucleoplasm. Orthologous to human DRG2 (developmentally regulated GTP binding protein 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Drg2
Official Name
developmentally regulated GTP binding protein 2 [Source:RGD Symbol;Acc:1562380]
Ensembl ID
ENSRNOG00000055309
Bio databases IDs NCBI: 497915 Ensembl: ENSRNOG00000055309
Aliases developmentally regulated GTP binding protein 2
Synonyms developmentally regulated GTP binding protein 2, RGD1562380
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Drg2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • GTP binding
  • TGS domain
  • small GTP-binding protein domain
  • Ubl1_cv_Nsp3_N-like
  • 50S ribosome-binding GTPase
  • GTPase
  • enzyme
  • protein binding
  • C-terminal region of MMR_HSR1 domain
  • P-loop containing Nucleoside Triphosphate Hydrolases
  • RNA binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • SUP-T1 cells
  • GLI1
  • CEMss cells
  • CEMfh cells
  • SP1
  • CEM cells
  • phytohemagglutinin
  • Jurkat E6.1 cells
disease
  • breast carcinoma
role in cell
  • survival
  • fusion
  • cell spreading

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • intracellular membrane-bounded organelle
  • Nucleus
  • cytosol
  • nucleoplasm
  • plasma

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Drg2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • signal transduction
  • cytoplasmic translation

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm
  • intracellular membrane-bounded organelle
  • membrane
  • cytosol
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • GTP binding
  • RNA binding
  • protein binding
  • metal ion binding
  • GTPase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.