KANSL3 Gene Summary [Human]
Involved in histone H4-K16 acetylation; histone H4-K5 acetylation; and histone H4-K8 acetylation. Located in nucleoplasm. Part of histone acetyltransferase complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | KANSL3 |
| Official Name | KAT8 regulatory NSL complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:25473] |
| Ensembl ID | ENSG00000114982 |
| Bio databases IDs | |
| Aliases | KAT8 regulatory NSL complex subunit 3 |
| Synonyms | 4632411B12Rik, 4932435K23, FLJ10081, KAT8 regulatory NSL complex subunit 3, KIAA1310, mKIAA1310, NSL3, Rcd1, RGD1309220 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human KANSL3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- intracellular membrane-bounded organelle
- Mitochondria
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human KANSL3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of transcription, DNA-dependent
- chromatin organization
- positive regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- intracellular membrane-bounded organelle
- mitochondrion
- NSL complex
- nucleoplasm
- histone acetyltransferase complex