CLIP4 Gene Summary [Human]

Predicted to enable microtubule plus-end binding activity. Predicted to be involved in cytoplasmic microtubule organization. Located in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
CLIP4
Official Name
CAP-Gly domain containing linker protein family member 4 [Source:HGNC Symbol;Acc:HGNC:26108]
Ensembl ID
ENSG00000115295
Bio databases IDs NCBI: 79745 Ensembl: ENSG00000115295
Aliases CAP-Gly domain containing linker protein family member 4
Synonyms 1700024K14Rik, 1700074B05Rik, 4833417L20Rik, 5830409B12Rik, CAP-Gly domain containing linker protein family member 4, CAP-GLY domain containing linker protein family, member 4, LOC108353550, LOC120093199, LOC120103484, RGD1311049, RSNL2
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CLIP4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Ankyrin repeats (many copies)
  • CAP-Gly domain
  • Ankyrin repeats (3 copies)
  • protein binding
  • CAP_GLY
  • Ankyrin repeat

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • HER2 negative hormone receptor negative breast cancer
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • intracellular membrane-bounded organelle

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human CLIP4 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cytoplasmic microtubule organization

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • microtubule plus end
  • intracellular membrane-bounded organelle
  • cell cortex

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • microtubule plus-end binding

Gene-Specific Assays for Results You Can Trust

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