PECR Gene Summary [Human]
Enables signaling receptor binding activity and trans-2-enoyl-CoA reductase (NADPH) activity. Involved in phytol metabolic process. Located in peroxisome. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | PECR |
| Official Name | peroxisomal trans-2-enoyl-CoA reductase [Source:HGNC Symbol;Acc:HGNC:18281] |
| Ensembl ID | ENSG00000115425 |
| Bio databases IDs | |
| Aliases | peroxisomal trans-2-enoyl-CoA reductase, short chain dehydrogenase/reductase family 29C, member 1 |
| Synonyms | 2400003B18Rik, 2-enoyl-coa Reductase, DCRRP, HPDHASE, HSA250303, Peroxisomal Trans 2-Enoyl Coa Reductase, PVIARL, SDR29C1, TERP |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PECR often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- 2-deoxy-D-gluconate 3-dehydrogenase
- Rossmann-fold NAD(P)(+)-binding proteins
- sepiapterin reductase
- acetoin reductases
- pteridine reductase
- enzyme
- Enoyl-(Acyl carrier protein) reductase
- receptor binding
- short chain dehydrogenase
- Saccharopine dehydrogenase NADP binding domain
- trans-2-enoyl-CoA reductase (NADPH2)
- 3-oxoacyl-(acyl-carrier-protein) reductase, putative
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intracellular membrane-bounded organelle
- Mitochondria
- cytosol
- peroxisome membrane
- peroxisomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human PECR gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- fatty acid biosynthetic process
- phytol metabolic process
Cellular Component
Where in the cell the gene product is active
- peroxisomal membrane
- peroxisome
- mitochondrion
- cytosol
Molecular Function
What the gene product does at the molecular level
- 2,4-dienoyl-CoA reductase (NADPH) activity
- trans-2-enoyl-CoA reductase (NADPH) activity
- receptor binding