RMDN2 Gene Summary [Human]

Enables microtubule binding activity. Located in Golgi apparatus; cytosol; and spindle. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
RMDN2
Official Name
regulator of microtubule dynamics 2 [Source:HGNC Symbol;Acc:HGNC:26567]
Ensembl ID
ENSG00000115841
Bio databases IDs NCBI: 151393 Ensembl: ENSG00000115841
Aliases regulator of microtubule dynamics 2
Synonyms 4921513D11RIK, BLOCK18, FAM82A, FAM82A1, LOC100502965, mRMD-2, PRO34163, PYST9371, regulator of microtubule dynamics 2, RMD-2, RMD4
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RMDN2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • microtubule binding
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • esophageal carcinoma
  • melanoma cancer
  • prostate cancer
  • Alzheimer disease
  • prostatic carcinoma
  • epithelial cancer
  • melanoma
  • impotence
  • cutaneous melanoma
  • cutaneous melanoma cancer
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Golgi Apparatus
  • Mitochondria
  • cytosol
  • spindle pole
  • spindle fibers
  • mitotic spindle

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human RMDN2 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • spindle microtubule
  • mitotic spindle
  • cytoplasm
  • membrane
  • mitochondrion
  • cytosol
  • Golgi apparatus

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • microtubule binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.