SCAMP3 Gene Summary [Human]

This gene encodes an integral membrane protein that belongs to the secretory carrier membrane protein family. The encoded protein functions as a carrier to the cell surface in post-golgi recycling pathways. This protein is also involved in protein trafficking in endosomal pathways. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2011]

Details

Type
Processed Transcript
Official Symbol
SCAMP3
Official Name
secretory carrier membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:10565]
Ensembl ID
ENSG00000116521
Bio databases IDs NCBI: 10067 Ensembl: ENSG00000116521
Aliases secretory carrier membrane protein 3, Propin 1
Synonyms C1orf3, LOC115489, secretory carrier membrane protein 3
Species
Human, Homo sapiens
OrthologiesRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SCAMP3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • ubiquitin protein ligase binding
  • SCAMP family
  • PSAP motif

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • inflammatory bowel disease
  • Crohn disease
regulated by
regulates
role in cell
  • growth
  • degradation in
  • transport

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • intracellular membrane-bounded organelle
  • cell surface
  • perinuclear region
  • cellular membrane
  • Plasma Membrane
  • Golgi Apparatus
  • Golgi membrane
  • trans Golgi network
  • recycling endosomes

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human SCAMP3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein transport
  • post-Golgi vesicle-mediated transport

Cellular Component

Where in the cell the gene product is active
  • extracellular vesicular exosome
  • intracellular membrane-bounded organelle
  • recycling endosome membrane
  • trans-Golgi network membrane

Molecular Function

What the gene product does at the molecular level
  • ubiquitin protein ligase binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.