SUPT7L Gene Summary [Human]
SUPT7L is a protein subunit of the human STAGA complex (SPT3; (MIM 602947)/TAF9 (MIM 600822)/GCN5 (MIM 602301) acetyltransferase complex), which is a chromatin-modifying multiprotein complex (Martinez et al., 2001 [PubMed 11564863]).[supplied by OMIM, Apr 2009]
Details
| Type | Protein Coding |
| Official Symbol | SUPT7L |
| Official Name | SPT7 like, STAGA complex subunit gamma [Source:HGNC Symbol;Acc:HGNC:30632] |
| Ensembl ID | ENSG00000119760 |
| Bio databases IDs | |
| Aliases | SPT7 like, STAGA complex subunit gamma |
| Synonyms | 2610524B01RIK, 6030455L14Rik, ART1, RGD1562206, SPT7L, SPT7-like, STAGA complex gamma subunit, SPT7 like, STAGA complex subunit gamma, SPT7 like, STAGA complex subunit γ, SPT7-like, STAGA complex γ subunit, STAF65, STAF65G, Staf65 gamma, STAF65(gamma), Staf65 γ, STAF65(γ), SUPT7H |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SUPT7L often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- histone fold domain (HFD) superfamily
- transcription regulator
- transcription co-activator
- protein binding
- Bromodomain associated
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SUPT7L gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of transcription, DNA-dependent
- regulation of DNA repair
- regulation of RNA splicing
- maintenance of protein location in nucleus
Cellular Component
Where in the cell the gene product is active
- nucleus
- SAGA complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- transcription coactivator activity
- protein heterodimerization activity