Supt7l Gene Summary [Mouse]
Predicted to enable transcription coactivator activity. Predicted to be involved in maintenance of protein location in nucleus. Predicted to be located in nucleoplasm. Predicted to be part of SAGA complex. Is expressed in brain; central nervous system ganglion; and sensory organ. Orthologous to human SUPT7L (SPT7 like, STAGA complex subunit gamma). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Supt7l |
| Official Name | SPT7-like, STAGA complex gamma subunit [Source:MGI Symbol;Acc:MGI:1919445] |
| Ensembl ID | ENSMUSG00000053134 |
| Bio databases IDs | |
| Aliases | SPT7-like, STAGA complex gamma subunit |
| Synonyms | 2610524B01RIK, 6030455L14Rik, ART1, RGD1562206, SPT7L, SPT7-like, STAGA complex gamma subunit, SPT7 like, STAGA complex subunit gamma, SPT7 like, STAGA complex subunit γ, SPT7-like, STAGA complex γ subunit, STAF65, STAF65G, Staf65 gamma, STAF65(gamma), Staf65 γ, STAF65(γ), SUPT7H |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Supt7l often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- histone fold domain (HFD) superfamily
- transcription regulator
- transcription co-activator
- protein binding
- Bromodomain associated
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Supt7l gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of transcription, DNA-dependent
- regulation of DNA repair
- regulation of RNA splicing
- maintenance of protein location in nucleus
Cellular Component
Where in the cell the gene product is active
- nucleus
- SAGA complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- transcription coactivator activity
- protein heterodimerization activity