A1BG Gene Summary [Human]
The protein encoded by this gene is a plasma glycoprotein of unknown function. The protein shows sequence similarity to the variable regions of some immunoglobulin supergene family member proteins. [provided by RefSeq, Jul 2008]
Details
| Type | Processed Transcript |
| Official Symbol | A1BG |
| Official Name | alpha-1-B glycoprotein [Source:HGNC Symbol;Acc:HGNC:5] |
| Ensembl ID | ENSG00000121410 |
| Bio databases IDs | |
| Aliases | alpha-1-B glycoprotein |
| Synonyms | A1B, ABG, alpha-1-beta-GLYCOPROTEIN, alpha-1-B glycoprotein, C44, GAB, Glycoprotein ib-α, HYST2477, α-1-B glycoprotein, α-1-β-GLYCOPROTEIN |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human A1BG often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- immunoglobulin domain
- Immunoglobulin like
Pathways
Biological processes and signaling networks where the A1BG gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- annulus
- secretory granule lumen
- ficolin-1-rich granule lumen
- alpha granules
- acrosome
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human A1BG gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- immune response-regulating signaling pathway
Cellular Component
Where in the cell the gene product is active
- platelet alpha granule lumen
- extracellular space
- extracellular vesicular exosome
- blood microparticle
- secretory granule lumen
- extracellular region
- plasma membrane