icon_0328_cc_gen_hmr_bacteria-s

FXR/RXR Activation

The farnesoid X receptor (FXR) is a member of the nuclear family of receptors and has emerged as a key player in the control of numerous metabolic pathways. Bile acids and their intermediates activate FXR, which thus serves as a sensor of bile acid levels. Along with retinoid X receptor (RXR), FXR plays a crucial role in linking bile acid regulation with lipoprotein, lipid and glucose metabolism. The concentration of bile acids and their intermediates can be elevated in conditions like cholestasis or inborn metabolic disorders. The metabolic syndrome is characterized by insulin resistance and glucose tolerance, abdominal obesity, hypertension, low high-density lipoproteins (HDL) and hypertriglyceridemia...

FXR/RXR Activation

Pathway Summary

The farnesoid X receptor (FXR) is a member of the nuclear family of receptors and has emerged as a key player in the control of numerous metabolic pathways. Bile acids and their intermediates activate FXR, which thus serves as a sensor of bile acid levels. Along with retinoid X receptor (RXR), FXR plays a crucial role in linking bile acid regulation with lipoprotein, lipid and glucose metabolism. The concentration of bile acids and their intermediates can be elevated in conditions like cholestasis or inborn metabolic disorders. The metabolic syndrome is characterized by insulin resistance and glucose tolerance, abdominal obesity, hypertension, low high-density lipoproteins (HDL) and hypertriglyceridemia. As a modulator of bile, lipid and glucose homeostasis, FXR is an interesting pharmacological target for therapeutic applications.

FXR/RXR Activation Genes list

Explore Genes related to FXR/RXR Activation

Products related to FXR/RXR Activation

Explore products related to FXR/RXR Activation
GeneGlobe ID: SBHS-006Z | Cat. No.: 249950 | QuantiNova LNA PCR Focus Panels
QuantiNova LNA PCR Focus Panel Human Glucose Metabolism
QuantiNova LNA PCR Focus Panel
Product Specification
Copy Details
GeneGlobe ID: SBHS-017Z | Cat. No.: 249950 | QuantiNova LNA PCR Focus Panels
QuantiNova LNA PCR Focus Panel Human Obesity
QuantiNova LNA PCR Focus Panel
Product Specification
Copy Details
GeneGlobe ID: UPHS-056Z | Cat. No.: 249955 | QuantiNova LNA Probe PCR Focus Panels
QuantiNova LNA Probe PCR Focus Panel Human Nuclear Receptors & Coregulators
QuantiNova LNA Probe PCR Focus Panel
Product Specification
Copy Details
GeneGlobe ID: PAHS-017Z | Cat. No.: 330231 | RT2 Profiler PCR Arrays
RT² Profiler™ PCR Array Human Obesity
RT2 Profiler PCR Array
Product Specification
Copy Details
GeneGlobe ID: PAHS-080Z | Cat. No.: 330231 | RT2 Profiler PCR Arrays
RT² Profiler™ PCR Array Human Lipoprotein Signaling & Cholesterol Metabolism
RT2 Profiler PCR Array
Product Specification
Copy Details
GeneGlobe ID: UPHS-006Z | Cat. No.: 249955 | QuantiNova LNA Probe PCR Focus Panels
QuantiNova LNA Probe PCR Focus Panel Human Glucose Metabolism
QuantiNova LNA Probe PCR Focus Panel
Product Specification
Copy Details
GeneGlobe ID: UPHS-080Z | Cat. No.: 249955 | QuantiNova LNA Probe PCR Focus Panels
QuantiNova LNA Probe PCR Focus Panel Human Lipoprotein Signaling & Cholesterol Metabolism
QuantiNova LNA Probe PCR Focus Panel
Product Specification
Copy Details
GeneGlobe ID: UPHS-007Z | Cat. No.: 249955 | QuantiNova LNA Probe PCR Focus Panels
QuantiNova LNA Probe PCR Focus Panel Human Fatty Acid Metabolism
QuantiNova LNA Probe PCR Focus Panel
Product Specification
Copy Details
GeneGlobe ID: PAHS-007Z | Cat. No.: 330231 | RT2 Profiler PCR Arrays
RT² Profiler™ PCR Array Human Fatty Acid Metabolism
RT2 Profiler PCR Array
Product Specification
Copy Details
GeneGlobe ID: UPHS-017Z | Cat. No.: 249955 | QuantiNova LNA Probe PCR Focus Panels
QuantiNova LNA Probe PCR Focus Panel Human Obesity
QuantiNova LNA Probe PCR Focus Panel
Product Specification
Copy Details
GeneGlobe ID: SBHS-056Z | Cat. No.: 249950 | QuantiNova LNA PCR Focus Panels
QuantiNova LNA PCR Focus Panel Human Nuclear Receptors & Coregulators
QuantiNova LNA PCR Focus Panel
Product Specification
Copy Details
GeneGlobe ID: SBHS-080Z | Cat. No.: 249950 | QuantiNova LNA PCR Focus Panels
QuantiNova LNA PCR Focus Panel Human Lipoprotein Signaling & Cholesterol Metabolism
QuantiNova LNA PCR Focus Panel
Product Specification
Copy Details
GeneGlobe ID: PAHS-056Z | Cat. No.: 330231 | RT2 Profiler PCR Arrays
RT² Profiler™ PCR Array Human Nuclear Receptors & Coregulators
RT2 Profiler PCR Array
Product Specification
Copy Details
GeneGlobe ID: PAHS-006Z | Cat. No.: 330231 | RT2 Profiler PCR Arrays
RT² Profiler™ PCR Array Human Glucose Metabolism
RT2 Profiler PCR Array
Product Specification
Copy Details
GeneGlobe ID: SBHS-007Z | Cat. No.: 249950 | QuantiNova LNA PCR Focus Panels
QuantiNova LNA PCR Focus Panel Human Fatty Acid Metabolism
QuantiNova LNA PCR Focus Panel
Product Specification
Copy Details

Didn't find what you're looking for?

Discover other products relevant to this gene list with our Panel Finder. Check it out.