A1bg Gene Summary [Mouse]

Acts upstream of or within growth hormone receptor signaling pathway. Predicted to be located in extracellular region. Predicted to be active in plasma membrane. Orthologous to human A1BG (alpha-1-B glycoprotein). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Processed Transcript
Official Symbol
A1bg
Official Name
alpha-1-B glycoprotein [Source:MGI Symbol;Acc:MGI:2152878]
Ensembl ID
ENSMUSG00000022347
Bio databases IDs NCBI: 117586 Ensembl: ENSMUSG00000022347
Aliases alpha-1-B glycoprotein
Synonyms A1B, ABG, alpha-1-beta-GLYCOPROTEIN, alpha-1-B glycoprotein, C44, GAB, Glycoprotein ib-α, HYST2477, α-1-B glycoprotein, α-1-β-GLYCOPROTEIN
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse A1bg often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • immunoglobulin domain
  • Immunoglobulin like

Pathways

Biological processes and signaling networks where the A1bg gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • liver cancer
  • rheumatoid arthritis
  • cholangiocarcinoma
  • cholangiocarcinoma cancer
  • ovarian cancer
regulated by
regulates

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • annulus
  • secretory granule lumen
  • ficolin-1-rich granule lumen
  • alpha granules
  • acrosome
  • plasma

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse A1bg gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • immune response-regulating signaling pathway

Cellular Component

Where in the cell the gene product is active
  • platelet alpha granule lumen
  • extracellular space
  • extracellular vesicular exosome
  • blood microparticle
  • secretory granule lumen
  • extracellular region
  • plasma membrane

Gene-Specific Assays for Results You Can Trust

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