CLCC1 Gene Summary [Human]
Predicted to enable chloride channel activity. Predicted to be involved in chloride transport. Located in endoplasmic reticulum and mitochondria-associated endoplasmic reticulum membrane. Implicated in retinitis pigmentosa 32. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | CLCC1 |
| Official Name | chloride channel CLIC like 1 [Source:HGNC Symbol;Acc:HGNC:29675] |
| Ensembl ID | ENSG00000121940 |
| Bio databases IDs | |
| Aliases | chloride channel CLIC like 1, Mid1-related chloride channel (yeast) |
| Synonyms | chloride channel CLIC-like 1, ERAC1, KIAA0761, MCLC, RP32 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CLCC1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Mid-1-related chloride channel (MCLC)
- chloride channel
- protein binding
- identical protein binding
- ion channel
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- endoplasmic reticulum mitochondria contact site
- intracellular membrane-bounded organelle
- perinuclear region
- Nucleus
- Golgi Apparatus
- Endoplasmic Reticulum
- endoplasmic reticulum membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CLCC1 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- chloride channel complex
- endoplasmic reticulum membrane
- nuclear membrane
- intracellular membrane-bounded organelle
- membrane
- ER-mitochondrion membrane contact site
- endoplasmic reticulum
- Golgi membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- chloride channel activity