RMDN3 Gene Summary [Human]
Enables microtubule binding activity. Involved in cellular calcium ion homeostasis. Located in several cellular components, including intercellular bridge; mitochondrial outer membrane; and spindle. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | RMDN3 |
| Official Name | regulator of microtubule dynamics 3 [Source:HGNC Symbol;Acc:HGNC:25550] |
| Ensembl ID | ENSG00000137824 |
| Bio databases IDs | |
| Aliases | regulator of microtubule dynamics 3 |
| Synonyms | 1200015F23Rik, FAM82A2, FAM82C, FLJ10579, LOC100911313, Ptpip51, regulator of microtubule dynamics 3, RGD1308697, RMD-3 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RMDN3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- microtubule binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- glutaminergic synapse
- presynaptic regions
- postsynaptic region
- Mitochondria
- cytoplasmic bridges
- mitochondrial outer membrane
- spindle pole
- spindle fibers
- organelle membrane contact site
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RMDN3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- apoptotic process
- cell differentiation
- cellular calcium ion homeostasis
Cellular Component
Where in the cell the gene product is active
- nucleus
- spindle microtubule
- intercellular bridge
- cytoplasm
- organelle membrane contact site
- mitochondrion
- mitochondrial outer membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- microtubule binding