RPRM Gene Summary [Human]
Predicted to be involved in regulation of mitotic cell cycle. Predicted to act upstream of or within regulation of cell cycle. Predicted to be integral component of membrane. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | RPRM |
| Official Name | reprimo, TP53 dependent G2 arrest mediator homolog [Source:HGNC Symbol;Acc:HGNC:24201] |
| Ensembl ID | ENSG00000177519 |
| Bio databases IDs | |
| Aliases | reprimo, TP53 dependent G2 arrest mediator homolog, candidate mediator of the p53 dependent G2 arrest, REPRIMO |
| Synonyms | 2410012A13Rik, REPRIMO, reprimo, TP53 dependent G2 arrest mediator candidate, reprimo, TP53 dependent G2 arrest mediator homolog |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RPRM often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Pathways
Biological processes and signaling networks where the RPRM gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- cognitive impairment
role in cell
- phosphorylation in
- cell viability
- proliferation
- expression in
- growth
- degradation in
- apoptosis
- cell cycle progression
- G2 phase
- damage in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cell surface
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RPRM gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of cell cycle
- regulation of mitotic cell cycle
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- membrane
Molecular Function
What the gene product does at the molecular level
- protein binding