SLC2A4RG Gene Summary [Human]
The protein encoded by this gene is a nuclear transcription factor involved in the activation of the solute carrier family 2 member 4 gene. The encoded protein interacts with another transcription factor, myocyte enhancer factor 2, to activate transcription of this gene. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | SLC2A4RG |
| Official Name | SLC2A4 regulator [Source:HGNC Symbol;Acc:HGNC:15930] |
| Ensembl ID | ENSG00000125520 |
| Bio databases IDs | |
| Aliases | SLC2A4 regulator, GLUT4 enhancer factor, Huntington's disease gene regulatory region-binding protein 1 |
| Synonyms | GEF, HDBP-1, Si-1-2, Si-1-2-19, SLC2A4 regulator |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SLC2A4RG often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- DNA binding domain
- transcription factor activity
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- nuclear fraction
- Nucleus
- nuclear speckles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SLC2A4RG gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of transcription, DNA-dependent
- regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- nuclear speck
Molecular Function
What the gene product does at the molecular level
- sequence-specific DNA binding transcription factor activity
- metal ion binding
- RNA polymerase II core promoter proximal region sequence-specific DNA binding