ZNF410 Gene Summary [Human]

Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
ZNF410
Official Name
zinc finger protein 410 [Source:HGNC Symbol;Acc:HGNC:20144]
Ensembl ID
ENSG00000119725
Bio databases IDs NCBI: 57862 Ensembl: ENSG00000119725
Aliases zinc finger protein 410
Synonyms APA-1, D12Ertd748e, Zfp410, zinc finger protein 410
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ZNF410 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Zinc finger, C2H2 type
  • zinc finger
  • transcription regulator
  • double-stranded DNA binding
  • nucleic acid binding
  • Zinc-finger double domain
  • protein binding
  • sequence-specific DNA binding
  • transcription factor activity
  • C2H2-type zinc ribbon
  • C2H2-type zinc finger

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
regulates
  • SERPINB2
  • RNA polymerase II
  • DNA promoter
  • DNA endogenous promoter
  • MMP1

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human ZNF410 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • negative regulation of gene expression
  • positive regulation of transcription from RNA polymerase II promoter
  • regulation of transcription from RNA polymerase II promoter

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • chromosome

Molecular Function

What the gene product does at the molecular level
  • sequence-specific DNA binding transcription factor activity
  • transcription cofactor activity
  • protein binding
  • metal ion binding
  • RNA polymerase II core promoter proximal region sequence-specific DNA binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.