EPB41L4A Gene Summary [Human]
The protein encoded by this gene is a member of the band 4.1 protein superfamily. Members of this superfamily are thought to play an important role in regulating interactions between the cytoskeleton and plasma membrane, and contain an amino terminal conserved domain that binds glycophorin C. This gene product is thought to be involved in the beta-catenin signaling pathway. [provided by RefSeq, Dec 2016]
Details
| Type | Processed Transcript |
| Official Symbol | EPB41L4A |
| Official Name | erythrocyte membrane protein band 4.1 like 4A [Source:HGNC Symbol;Acc:HGNC:13278] |
| Ensembl ID | ENSG00000129595 |
| Bio databases IDs | |
| Aliases | erythrocyte membrane protein band 4.1 like 4A |
| Synonyms | EPB41L4, Epb4.1l4, Epb4.1l4a, erythrocyte membrane protein band 4.1 like 4A, NBL4 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human EPB41L4A often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- FERM adjacent (FA)
- FERM central domain
- Band 4.1 homologues
- Ubl1_cv_Nsp3_N-like
- Pleckstrin homology-like domain
- FERM domain B-lobe
- FERM C-terminal PH-like domain
- FERM N-terminal domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human EPB41L4A gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- actomyosin structure organization
Cellular Component
Where in the cell the gene product is active
- cytoskeleton
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- cytoskeletal protein binding