Epb41l4a Gene Summary [Rat]

Predicted to enable cytoskeletal protein binding activity. Predicted to be involved in actomyosin structure organization. Predicted to be active in cytoskeleton. Orthologous to human EPB41L4A (erythrocyte membrane protein band 4.1 like 4A). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Epb41l4a
Official Name
erythrocyte membrane protein band 4.1 like 4A [Source:RGD Symbol;Acc:1306034]
Ensembl ID
ENSRNOG00000026050
Bio databases IDs NCBI: 307514 Ensembl: ENSRNOG00000026050
Aliases erythrocyte membrane protein band 4.1 like 4A
Synonyms EPB41L4, Epb4.1l4, Epb4.1l4a, erythrocyte membrane protein band 4.1 like 4A, NBL4
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Epb41l4a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • FERM adjacent (FA)
  • FERM central domain
  • Band 4.1 homologues
  • Ubl1_cv_Nsp3_N-like
  • Pleckstrin homology-like domain
  • FERM domain B-lobe
  • FERM C-terminal PH-like domain
  • FERM N-terminal domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • neuroblastoma
  • neuroblastoma formation
  • dementia
  • thyroid cancer
  • epithelial thyroid cancer
  • thyroid carcinoma
  • insomnia
  • sarcopenia
  • early missed abortion
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Epb41l4a gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • actomyosin structure organization

Cellular Component

Where in the cell the gene product is active
  • cytoskeleton
  • cytoplasm

Molecular Function

What the gene product does at the molecular level
  • cytoskeletal protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.