REEP5 Gene Summary [Human]
Predicted to be involved in endoplasmic reticulum organization and regulation of intracellular transport. Located in endoplasmic reticulum tubular network. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | REEP5 |
| Official Name | receptor accessory protein 5 [Source:HGNC Symbol;Acc:HGNC:30077] |
| Ensembl ID | ENSG00000129625 |
| Bio databases IDs | |
| Aliases | receptor accessory protein 5, deleted in polyposis 1, polyposis locus protein 1, polyposis coli region hypothetical protein DP1 |
| Synonyms | C5orf18, D5S346, DELETED IN POLYPOSIS, DP1, DP1/TB2, POB16, receptor accessory protein 5, TB2, TB2/DP1, Yip2e, YOP1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human REEP5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- TB2/DP1, HVA22 family
- protein binding
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- diabetic nephropathy
- aortic valve calcification
- attention deficit hyperactivity disorder
regulates
role in cell
- organization
- formation
- formation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- endoplasmic reticulum tubules
- cellular membrane
- sarcoplasmic reticulum
- Endoplasmic Reticulum
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human REEP5 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- endoplasmic reticulum membrane organization
- regulation of intracellular transport
- endoplasmic reticulum organization
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum tubular network
- endoplasmic reticulum
- sarcoplasmic reticulum membrane
Molecular Function
What the gene product does at the molecular level
- protein binding