RCE1 Gene Summary [Human]
This gene encodes an integral membrane protein which is classified as a member of the metalloproteinase family. This enzyme is thought to function in the maintenance and processing of CAAX-type prenylated proteins. [provided by RefSeq, Jul 2008]
Details
| Type | Retained Intron |
| Official Symbol | RCE1 |
| Official Name | Ras converting CAAX endopeptidase 1 [Source:HGNC Symbol;Acc:HGNC:13721] |
| Ensembl ID | ENSG00000173653 |
| Bio databases IDs | |
| Aliases | Ras converting CAAX endopeptidase 1, farnesylated protein-converting enzyme 2, prenyl protein-specific endoprotease 2, RCE1 homolog, prenyl protein protease, CAAX prenyl protease 2 |
| Synonyms | D19Ertd283e, D19Ertd98e, FACE2, FARNESYLATED PROTEINS CONVERTING ENZYME 2, Ras converting CAAX endopeptidase 1, RCE1A, RCE1B |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RCE1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- endopeptidase
- cysteine endopeptidase
- Type II CAAX prenyl endopeptidase Rce1-like
- peptidase
- exopeptidase
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Plasma Membrane
- cytosol
- endoplasmic reticulum membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RCE1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- MAPK cascade
- CAAX-box protein processing
- protein prenylation
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- membrane
- cytosol
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- endopeptidase activity
- cysteine-type endopeptidase activity
- metalloendopeptidase activity
- exopeptidase activity