Reep5 Gene Summary [Rat]
Predicted to be involved in endoplasmic reticulum membrane organization. Predicted to be located in endoplasmic reticulum tubular network and junctional sarcoplasmic reticulum membrane. Orthologous to human REEP5 (receptor accessory protein 5). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Reep5 |
| Official Name | receptor accessory protein 5 [Source:RGD Symbol;Acc:1306047] |
| Ensembl ID | ENSRNOG00000020167 |
| Bio databases IDs | |
| Aliases | receptor accessory protein 5 |
| Synonyms | C5orf18, D5S346, DELETED IN POLYPOSIS, DP1, DP1/TB2, POB16, receptor accessory protein 5, TB2, TB2/DP1, Yip2e, YOP1 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Reep5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- TB2/DP1, HVA22 family
- protein binding
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- diabetic nephropathy
- aortic valve calcification
- attention deficit hyperactivity disorder
regulates
role in cell
- organization
- formation
- formation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- endoplasmic reticulum tubules
- cellular membrane
- sarcoplasmic reticulum
- Endoplasmic Reticulum
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Reep5 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- endoplasmic reticulum membrane organization
- regulation of intracellular transport
- endoplasmic reticulum organization
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum tubular network
- endoplasmic reticulum
- sarcoplasmic reticulum membrane
Molecular Function
What the gene product does at the molecular level
- protein binding