SEC14L1 Gene Summary [Human]
The protein encoded by this gene belongs to the SEC14 cytosolic factor family. It has similarity to yeast SEC14 and to Japanese flying squid RALBP which suggests a possible role of the gene product in an intracellular transport system. Multiple alternatively spliced transcript variants have been found for this gene; some variants represent read-through transcripts that include exons from the upstream gene C17orf86. [provided by RefSeq, Feb 2011]
Details
| Type | Protein Coding |
| Official Symbol | SEC14L1 |
| Official Name | SEC14 like lipid binding 1 [Source:HGNC Symbol;Acc:HGNC:10698] |
| Ensembl ID | ENSG00000129657 |
| Bio databases IDs | |
| Aliases | SEC14 like lipid binding 1 |
| Synonyms | 1200017E04Rik, 2810012L19Rik, Naa-35, PRELID4A, RGD1563123, SEC14L, SEC14-like lipid binding 1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SEC14L1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Domain in homologues of a S
- CRAL/TRIO, N-terminal domain
- CRAL/TRIO domain
- protein binding
- receptor binding
- transporter
- PRELI-like family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi Apparatus
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SEC14L1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- choline transport
- innate immune response
- negative regulation of RIG-I signaling pathway
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- cytosol
- Golgi apparatus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- RIG-I binding