Sec14l1 Gene Summary [Mouse]
Predicted to enable RIG-I binding activity and protein sequestering activity. Predicted to be involved in choline transport and negative regulation of RIG-I signaling pathway. Predicted to be located in nucleoplasm. Predicted to be active in cytosol. Predicted to colocalize with Golgi apparatus. Is expressed in cerebral cortex marginal layer and lung. Orthologous to human SEC14L1 (SEC14 like lipid binding 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Retained Intron |
| Official Symbol | Sec14l1 |
| Official Name | SEC14-like lipid binding 1 [Source:MGI Symbol;Acc:MGI:1921386] |
| Ensembl ID | ENSMUSG00000020823 |
| Bio databases IDs | |
| Aliases | SEC14-like lipid binding 1 |
| Synonyms | 1200017E04Rik, 2810012L19Rik, Naa-35, PRELID4A, RGD1563123, SEC14L, SEC14-like lipid binding 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Sec14l1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Domain in homologues of a S
- CRAL/TRIO, N-terminal domain
- CRAL/TRIO domain
- protein binding
- receptor binding
- transporter
- PRELI-like family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi Apparatus
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Sec14l1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- choline transport
- innate immune response
- negative regulation of RIG-I signaling pathway
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- cytosol
- Golgi apparatus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- RIG-I binding