NOL11 Gene Summary [Human]
Enables RNA binding activity. Involved in maturation of SSU-rRNA and positive regulation of transcription of nucleolar large rRNA by RNA polymerase I. Located in nucleolus. Part of t-UTP complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | NOL11 |
| Official Name | nucleolar protein 11 [Source:HGNC Symbol;Acc:HGNC:24557] |
| Ensembl ID | ENSG00000130935 |
| Bio databases IDs | |
| Aliases | nucleolar protein 11 |
| Synonyms | 1500002M01Rik, LOC108353670, LOC688235, nucleolar protein 11 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human NOL11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- NUC205 domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human NOL11 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- maturation of SSU-rRNA
Cellular Component
Where in the cell the gene product is active
- t-UTP complex
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding