Nol11 Gene Summary [Mouse]

Predicted to be involved in maturation of SSU-rRNA and positive regulation of transcription of nucleolar large rRNA by RNA polymerase I. Predicted to be part of t-UTP complex. Predicted to be active in nucleolus. Orthologous to human NOL11 (nucleolar protein 11). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Nol11
Official Name
nucleolar protein 11 [Source:MGI Symbol;Acc:MGI:1916229]
Ensembl ID
ENSMUSG00000018433
Bio databases IDs NCBI: 68979 Ensembl: ENSMUSG00000018433
Aliases nucleolar protein 11
Synonyms 1500002M01Rik, LOC108353670, LOC688235, nucleolar protein 11
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Nol11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • NUC205 domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • hypodontia
regulated by
role in cell
  • autophagy in
  • autophagy

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Nol11 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • maturation of SSU-rRNA

Cellular Component

Where in the cell the gene product is active
  • t-UTP complex
  • nucleolus
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • RNA binding
  • protein binding