ACTR10 Gene Summary [Human]
Predicted to be involved in retrograde axonal transport of mitochondrion. Predicted to be located in cytosol; extracellular region; and secretory granule. Predicted to be part of dynactin complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | ACTR10 |
| Official Name | actin related protein 10 [Source:HGNC Symbol;Acc:HGNC:17372] |
| Ensembl ID | ENSG00000131966 |
| Bio databases IDs | |
| Aliases | actin related protein 10 |
| Synonyms | actin related protein 10, ACTR11, Arp10, ARP10 actin-related protein 10, Arp11, FLJ12186, HARP11 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ACTR10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Actin
- protein binding
- ASKHA_ATPase-like
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- ficolin-1-rich granule lumen
- azurophil granule lumen
- Extracellular Space
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ACTR10 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- dynactin complex
- actin cytoskeleton
- cytosol
- extracellular region
- azurophil granule lumen
Molecular Function
What the gene product does at the molecular level
- protein binding