Actr10 Gene Summary [Rat]

Predicted to be involved in retrograde axonal transport of mitochondrion. Predicted to act upstream of or within microtubule-based movement. Predicted to be located in axon cytoplasm. Predicted to be part of dynactin complex. Orthologous to human ACTR10 (actin related protein 10). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Actr10
Official Name
actin related protein 10 [Source:RGD Symbol;Acc:1306515]
Ensembl ID
ENSRNOG00000007504
Bio databases IDs NCBI: 299121 Ensembl: ENSRNOG00000007504
Aliases actin related protein 10
Synonyms actin related protein 10, ACTR11, Arp10, ARP10 actin-related protein 10, Arp11, FLJ12186, HARP11
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Actr10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Actin
  • protein binding
  • ASKHA_ATPase-like

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-small cell lung cancer
  • non-small cell lung carcinoma
  • organismal death
  • non-melanoma skin cancer
  • progression free survival
regulated by
role in cell
  • movement by
  • movement

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • ficolin-1-rich granule lumen
  • azurophil granule lumen
  • Extracellular Space
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Actr10 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • dynactin complex
  • actin cytoskeleton
  • cytosol
  • extracellular region
  • azurophil granule lumen

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.