Actr10 Gene Summary [Mouse]

Acts upstream of or within microtubule-based movement. Part of dynactin complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human ACTR10 (actin related protein 10). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Actr10
Official Name
ARP10 actin-related protein 10 [Source:MGI Symbol;Acc:MGI:1891654]
Ensembl ID
ENSMUSG00000021076
Bio databases IDs NCBI: 56444 Ensembl: ENSMUSG00000021076
Aliases ARP10 actin-related protein 10
Synonyms actin related protein 10, ACTR11, Arp10, ARP10 actin-related protein 10, Arp11, FLJ12186, HARP11
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Actr10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Actin
  • protein binding
  • ASKHA_ATPase-like

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-small cell lung cancer
  • non-small cell lung carcinoma
  • organismal death
  • non-melanoma skin cancer
  • progression free survival
regulated by
role in cell
  • movement by
  • movement

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • ficolin-1-rich granule lumen
  • azurophil granule lumen
  • Extracellular Space
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Actr10 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • dynactin complex
  • actin cytoskeleton
  • cytosol
  • extracellular region
  • azurophil granule lumen

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.