TIMM10B Gene Summary [Human]
FXC1, or TIMM10B, belongs to a family of evolutionarily conserved proteins that are organized in heterooligomeric complexes in the mitochondrial intermembrane space. These proteins mediate the import and insertion of hydrophobic membrane proteins into the mitochondrial inner membrane.[supplied by OMIM, Apr 2004]
Details
| Type | Retained Intron |
| Official Symbol | TIMM10B |
| Official Name | translocase of inner mitochondrial membrane 10B [Source:HGNC Symbol;Acc:HGNC:4022] |
| Ensembl ID | ENSG00000132286 |
| Bio databases IDs | |
| Aliases | translocase of inner mitochondrial membrane 10B |
| Synonyms | FXC1, Gm45799, TIM10B, Tim9b, translocase of inner mitochondrial membrane 10B |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TIMM10B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Tim10/DDP family zinc finger
- protein binding
- transporter
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- pH resistant lipid raft fraction
- inner membrane
- Mitochondria
- mitochondrial intermembrane space
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TIMM10B gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell-matrix adhesion
- protein import into mitochondrial inner membrane
Cellular Component
Where in the cell the gene product is active
- mitochondrial intermembrane space
- mitochondrial intermembrane space protein transporter complex
- mitochondrial inner membrane
- mitochondrial inner membrane protein insertion complex
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding
- unfolded protein binding