TIMM9 Gene Summary [Human]
TIMM9 belongs to a family of evolutionarily conserved proteins that are organized in heterooligomeric complexes in the mitochondrial intermembrane space. These proteins mediate the import and insertion of hydrophobic membrane proteins into the mitochondrial inner membrane.[supplied by OMIM, Apr 2004]
Details
| Type | Protein Coding |
| Official Symbol | TIMM9 |
| Official Name | translocase of inner mitochondrial membrane 9 [Source:HGNC Symbol;Acc:HGNC:11819] |
| Ensembl ID | ENSG00000100575 |
| Bio databases IDs | |
| Aliases | translocase of inner mitochondrial membrane 9 |
| Synonyms | 2810011L15Rik, Tim10a, TIM9, TIM9A, Timm10, Timm9a, translocase of inner mitochondrial membrane 9 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TIMM9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- zinc ion binding
- protein homodimerization
- Tim10/DDP family zinc finger
- protein binding
- chaperone binding
- transporter
Pathways
Biological processes and signaling networks where the TIMM9 gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- inner membrane
- Mitochondria
- mitochondrial intermembrane space
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TIMM9 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein targeting to mitochondrion
- sensory perception of sound
- protein import into mitochondrial inner membrane
Cellular Component
Where in the cell the gene product is active
- mitochondrial intermembrane space
- mitochondrial intermembrane space protein transporter complex
- mitochondrion
- mitochondrial inner membrane
- mitochondrial inner membrane protein insertion complex
Molecular Function
What the gene product does at the molecular level
- zinc ion binding
- membrane insertase activity
- protein binding
- protein homodimerization activity
- chaperone binding