SDF2 Gene Summary [Human]
The protein encoded by this gene is believed to be a secretory protein. It has regions of similarity to hydrophilic segments of yeast mannosyltransferases. Its expression is ubiquitous and the gene appears to be relatively conserved among mammals. Alternate splicing results in both coding and non-coding variants. A pseudogene of this gene is located on chromosome 15. [provided by RefSeq, Dec 2011]
Details
| Type | Protein Coding |
| Official Symbol | SDF2 |
| Official Name | stromal cell derived factor 2 [Source:HGNC Symbol;Acc:HGNC:10675] |
| Ensembl ID | ENSG00000132581 |
| Bio databases IDs | |
| Aliases | stromal cell derived factor 2 |
| Synonyms | stromal cell derived factor 2 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SDF2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- MIR domain
- enzyme
- protein binding
- beta-trefoil_MIR
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Endoplasmic Reticulum
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SDF2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- chaperone mediated protein folding requiring cofactor
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum
Molecular Function
What the gene product does at the molecular level
- misfolded protein binding