Sdf2 Gene Summary [Rat]
Predicted to enable misfolded protein binding activity. Predicted to be involved in chaperone cofactor-dependent protein refolding. Predicted to be located in endoplasmic reticulum. Predicted to be part of protein folding chaperone complex. Orthologous to human SDF2 (stromal cell derived factor 2). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Sdf2 |
| Official Name | stromal cell derived factor 2 [Source:RGD Symbol;Acc:1307274] |
| Ensembl ID | ENSRNOG00000012121 |
| Bio databases IDs | |
| Aliases | stromal cell derived factor 2 |
| Synonyms | stromal cell derived factor 2 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Sdf2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- MIR domain
- enzyme
- protein binding
- beta-trefoil_MIR
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Endoplasmic Reticulum
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Sdf2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- chaperone mediated protein folding requiring cofactor
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum
Molecular Function
What the gene product does at the molecular level
- misfolded protein binding