Sdf2 Gene Summary [Mouse]

Predicted to enable misfolded protein binding activity. Predicted to be involved in chaperone cofactor-dependent protein refolding. Predicted to be located in endoplasmic reticulum. Predicted to be part of protein folding chaperone complex. Orthologous to human SDF2 (stromal cell derived factor 2). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Sdf2
Official Name
stromal cell derived factor 2 [Source:MGI Symbol;Acc:MGI:108019]
Ensembl ID
ENSMUSG00000002064
Bio databases IDs NCBI: 20316 Ensembl: ENSMUSG00000002064
Aliases stromal cell derived factor 2
Synonyms stromal cell derived factor 2
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Sdf2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • MIR domain
  • enzyme
  • protein binding
  • beta-trefoil_MIR

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • preeclampsia
regulated by
  • CGA
  • diethylstilbestrol
  • CD3 (complex)
  • DNAJB11
  • GnRH analog
  • NEF
  • mir-210

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • Endoplasmic Reticulum

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Sdf2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • chaperone mediated protein folding requiring cofactor

Cellular Component

Where in the cell the gene product is active
  • endoplasmic reticulum

Molecular Function

What the gene product does at the molecular level
  • misfolded protein binding

Gene-Specific Assays for Results You Can Trust

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