TMPRSS11B Gene Summary [Human]
Enables serine-type peptidase activity. Predicted to be involved in proteolysis. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | TMPRSS11B |
| Official Name | transmembrane serine protease 11B [Source:HGNC Symbol;Acc:HGNC:25398] |
| Ensembl ID | ENSG00000185873 |
| Bio databases IDs | |
| Aliases | transmembrane serine protease 11B, airway trypsin-like protease 5 |
| Synonyms | HATL5, Tmprss11bnl, transmembrane serine protease 11B |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TMPRSS11B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Trypsin-like serine protease
- trypsin
- Tryp_SPc
- serine-type peptidase
- peptidase
- SEA domain
Pathways
Biological processes and signaling networks where the TMPRSS11B gene in human plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TMPRSS11B gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- proteolysis
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- serine-type peptidase activity
- serine-type endopeptidase activity