NIP7 Gene Summary [Human]
Enables RNA binding activity. Predicted to be involved in ribosomal large subunit biogenesis. Located in cytosol; nucleolus; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Retained Intron |
| Official Symbol | NIP7 |
| Official Name | nucleolar pre-rRNA processing protein NIP7 [Source:HGNC Symbol;Acc:HGNC:24328] |
| Ensembl ID | ENSG00000132603 |
| Bio databases IDs | |
| Aliases | nucleolar pre-rRNA processing protein NIP7 |
| Synonyms | 1110017C15RIK, 6330509M23RIK, AA408773, CGI-37, HSPC031, KD93, NIP7, nucleolar pre-rRNA processing protein, Nip7p, nucleolar pre-rRNA processing protein NIP7, PEachy, Sacc cerer nip7p |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human NIP7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- PUA RNA binding domain
- UPF0113 Pre-PUA domain
- PUA domain
- UPF0113 PUA domain
- N-terminal domain of Nip7 and similar proteins
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cytosol
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human NIP7 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ribosomal large subunit biogenesis
- ribosome assembly
Cellular Component
Where in the cell the gene product is active
- cytosol
- nucleolus
- preribosome, large subunit precursor
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding